J Korean Ophthalmol Soc.  1992 Apr;33(4):410-414.

Aging Change of Pupil Size in Normal and Diabetic Patients

Affiliations
  • 1Department of Ophthalmology, Wonkwang University School of Medicine, Iri, Korea.
  • 2Department of Internal Medicine, Wonkwang University School of Medicine, Iri, Korea.

Abstract

It is well recognized that diabetic patients have small pupil. The most likely cause of the abnormally small pupil in diabetics is decreased funcitor of the autonomic nerves. We measured pupil size in 141 control subjects and 53 diabetic patients (29 cases with symptomatic autonomic neuropathy, 24 cases without symptomatic autonomic neuropathy) with portable pupillometry, PUPILSCAN in darkness. Pupils become smaller in healthy and diabetic subjects with advancing age. (log pupil size = 2.05 - 0.066 X age, r: -0.47, p

Keyword

Aging change; Autonomic europathy; Diabetes; Pupil size

MeSH Terms

Aging*
Autonomic Pathways
Darkness
Diabetic Neuropathies
Early Diagnosis
Humans
Miosis
Pupil*
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