Korean J Dermatol.
1999 Nov;37(11):1664-1666.
A Case of Chronic Bullous Dermatosis of Childhood: Implication for Duration of Dapsone Maintenance Therapy
- Affiliations
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- 1Department of Dermatology, Eulji Hospital, Eulji Medical College, College of Medicine, Seoul, Korea.
Abstract
- Chronic bullous dermatosis of childhood(CBDC) is a rare vesicobullous disorder in infancy and early childhood. The direct immunofluorescence(DIF) study is mandatory for diagnosis because its clinical and histological findings may be indistinguishable from those of bullous pemphigoid and dermatitis herpetiformis. The response to sulfonamides such as dapsone and sulfapyridine is usually rapid and complete. After remission of the disease, however, it is difficult to predict the course of the disease and to decide when treatment should be stopped. We report a case of CBDC in a 2-year-old boy. Treatment was started with dapsone and complete resolution of lesions was achieved in 2 weeks. The entire regimen was continued for 6 months and the patient has been clinically free of disease activity after 18 months of follow-up.
