Korean J Gastrointest Endosc.
2008 Jan;36(1):48-51.
A Case of Polypoid Ganglioneuroma of the Colon
- Affiliations
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- 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. inos@inha.ac.kr
- 2Department of Pathology, Inha University College of Medicine, Incheon, Korea.
Abstract
- A ganglioneuroma is a benign tumor composed of ganglion cells, nerve fibers, and supporting cells that originates from the neural crest. An occurrence of a ganglioneuroma is mainly along the pathway of the sympathetic chain. However, it is rare to find the lesion in the gastrointestinal tract. A ganglioneuroma of the gastrointestinal tract appears to involve predominantly the colon and rectum, but rarely involves the upper gastrointestinal tract. An intestinal ganglioneuroma is divided into three subgroups: a polypoid ganglioneuroma, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. A polypoid ganglioneuroma is not associated with systemic disease. However, ganglioneuromatous polyposis and diffuse ganglioneuromatosis are highly associated with systemic diseases. A 33-year-old woman who had no specific family history visited our institution with a complaint of abdominal discomfort. A single polyp was found incidentally in the descending colon during a colonoscopy and it was treated by snare polypectomy. The patient had no associated systemic disease and histology of the polyp revealed a ganglioneuroma. We report a patient with a polypoid ganglioneuroma of the colon.
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