J Korean Radiol Soc.  1999 Oct;41(4):739-744. 10.3348/jkrs.1999.41.4.739.

The Usefulness of CT and MR Virtual Colonoscopy in the Evaluation of Experimental Polyp Models

  • 1Department of Diagnostic Radiology Chonnam University Medical school.


PURPOSE: The purpose of this study was to evaluate the diagnostic accuracy of CT and MR virtual colonoscopy using an experimental model of colonic polyposis.
Eleven pig colons ranging from 15 to 20cm in length were cleansed and a total of 99 variable sized polyps ranging from 3 to 15mm in diameter were created. The polyps were divided into three groups according to size: <5mm(n=23), 5-9mm(n=44), and ?10mm(n=32) in diameter. Each specimen was scanned using spiral CT and MRI. Each CT and MR virtual colonoscopy was independently evaluated by two radiologists blinded to the location, size and numbers of polyps, but aware that polyps were present. Interobserver agreement regarding the detection rate of the polyps during the two types of virtual colonoscopy was measured and the diagnostic accuracy of CT and MR virtual colonoscopy was compared.
In both CT and MR virtual colonoscopy, the detection rates determined by the two radiologists coincided in all three groups(p<0.05). The detection rates of polyps less than 5mm, between 5 and 9mm, and 10mm or larger in diameter were 74%(17/23), 89%(39/44), and 100%(32/32), respectively, in CT colonoscopy, and 61%(14/23), 89%(39/44), and 100%(32/32), respectively in MR colonoscopy. In polyps 5mm or larger, the results of the two types of virtual colonscopy coincided but in those less than 5mm in diameter, the results of MR virtual colonoscopy were slightly inferior to those of CT colonoscopy.
Both CT and MR virtual colonoscopy provide high detection rates of colonic polyps 5mm or larger in diameter and these techniques can therefore be used to diagnose colonic mass lesions.


Colon, neoplasms; Computed tomography(CT), image processing; Computed tomography(CT), three-dimensional; Magnetic resonance(MR), image processing; Magnetic resonance(MR), three-dimensional
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