J Korean Radiol Soc.  1995 Jan;32(1):153-156.

Hepatoid Adenocarcinoma of the Stomach: A Case Report

• Yang I
• Lee Y
• Chung EA
• Chung SY
• Kirn JS

Abstract

Hepatoid adenocarcinoma of the stomach is a gastric carcinoma with both adenocarcinomatous and hepatocellular carcinomatous differentiation. It usually produces large amount of serum alpha-fetoprotein. It often occurs in aged person, commonly located in the gastric antrum. Because of early lymph node and liver metastasis, prognosis is poor. A case of hepatoid adenocarcinoma of the stomach in a 49-year-old man is reported. The patient's serum alpha-fetoprotein level was high(3380ng/ml). Liver function test was normal, otherwise. A mass was observed in right lobe of the liver on US and CT. It was hypervascular with increased uptake of lipiodol on hepatic arteriography. A large ulcerative tumor involving the gastric antrum and body was also found at barium study of the stomach. Subtotal gastrectomy and right Iobectomy of the liver resulted in rapid decrease in serum alpha-fetoprotein. Histopathologically the diagnosis was hepatoid adenocarcinoma of the stomach with liver metastasis.

MeSH Terms

Adenocarcinoma*
alpha-Fetoproteins
Angiography
Barium
Diagnosis
Ethiodized Oil
Gastrectomy
Humans
Liver
Liver Function Tests
Lymph Nodes
Middle Aged
Neoplasm Metastasis
Prognosis
Pyloric Antrum
Stomach*
Ulcer
Barium
Ethiodized Oil
alpha-Fetoproteins