J Korean Soc Coloproctol.  2005 Apr;21(2):71-75.

The Effect after Intra-dermal Methylene Blue, Hydrocortisone, Lidocaine Injection Therapy for Intractable, Idiopathic Pruritus Ani

• Kim JH
• Lee YP

Abstract

PURPOSE: Idiopathic pruritus ani is a common and embarrassing proctological condition which can be very difficult to treat. In this study, we documented our results with methylene blue intra-dermal injection in patients with intractable idiopathic pruritus ani.
METHODS
5-ml 1% methylene blue, 100-mg hydrocortisone, and 15-ml 1% lidocaine were injected into the perianal skin of 21 patients with idiopathic pruritus ani which had proved refractory to standard care. Clinical follow-up was undertaken.
RESULTS
After one injection of the above solution, 15 (71.4%) of the patients were rendered symptom free. Repeat injection in the initial non- responders ultimately rendered another four. 19 (total: 90.5 %) of the patrents symptom free. Morbidity was 0%.
CONCLUSION
This study has shown that intra-dermal methylene blue injection is a safe, simple, and efficient method of treating intractable, idiopathic pruritus ani.

Keyword

Idiopathic pruritus ani; Methylene blue; Intradermal injection therapy

MeSH Terms

Follow-Up Studies
Humans
Hydrocortisone*
Lidocaine*
Methylene Blue*
Pruritus Ani*
Pruritus*
Skin
Hydrocortisone
Lidocaine
Methylene Blue