J Korean Soc Neonatol.  2011 Nov;18(2):391-394. 10.5385/jksn.2011.18.2.391.

A Case of Neonatal Lupus Erythematosus and Retrospectively Diagnosed with Asymtomatic Maternal Lupus Erythematosus

Affiliations
  • 1Department of Pediatrics, College of Medicine, Konyang University, Daejeon, Korea. kokojh@hitel.net

Abstract

Neonatal lupus erythematosus (NLE) is a rare disease characterized by typical clinical features and the transplacental passage of maternal autoantibodies, particularly anti-SSA/Ro. The major clinical manifestations are cutaneous lupus lesions, congenital heart block, hematological disorders, and hepatobiliary diseases. We report a case of NLE presenting with multiple round and oval target-like erythematous skin lesions and abnormal liver function, born to a clinically asymptomatic mother whose diagnosis was made retrospectively only after her newborn's diagnosis. Both the infant and the mother were positive for the anti-SSA/Ro and anti-SSB/La antibodies.

Keyword

Neonatal lupus erythematosus; Erythema multifome; Asymptomatic; Maternal lupus

MeSH Terms

Antibodies
Autoantibodies
Heart Block
Humans
Infant
Liver
Lupus Erythematosus, Systemic
Mothers
Rare Diseases
Retrospective Studies
Skin
Antibodies
Autoantibodies
Heart Block
Lupus Erythematosus, Systemic
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