Korean J Anat.  2009 Jun;42(2):115-122.

Immunohistochemical Analysis of Calretinin and Parvalbumin in the Goat Main Olfactory Bulb

• Choi JH
• Lee CH
• Hwang IK
• Yoo KY
• Yoon YS
• Shin HC
• Lee IS
• Won MH

Abstract

The distributions of calretinin (CR)- and parvalbumin (PV)-immunoreactive neurons in the main olfactory bulb (MOB) of the goat were examined in this study. As in other animals, the goat MOB has a characteristic laminar structure with laminar types and distribution patterns in each layer. CR-immunoreaction was observed in all layers of the MOB, except for the olfactory nerve layer. Most of CR-immunoreactive neurons were observed in the glomerular and granule cell layers. Relatively small number of CR-immunoreactive neurons was detected in other layers. These CR-immunoreactive neurons were interneurons. PV-immunoreaction was detected in all layers. In contrast to CR, olfactory nerve bundles were immunostained with PV. Most of PV-immunoreactive neurons were distributed in the glomerular and granule cell layers. PV-immunoreactive neurons were interneurons. This result suggests that CR and PV may play important roles in the olfactory signal modulation through interneurons in the goat MOB.

Keyword

Calcium-binding proteins; Goat; Immunohistochemistry; Olfaction; Olfactory bulb

MeSH Terms

Animals
Calcium-Binding Protein, Vitamin D-Dependent
Calcium-Binding Proteins
Goats
Immunohistochemistry
Interneurons
Neurons
Olfactory Bulb
Olfactory Nerve
Smell
Calcium-Binding Protein, Vitamin D-Dependent
Calcium-Binding Proteins