Korean J Dermatol.  2011 Aug;49(8):730-734.

Primary Cutaneous Nocardiosis Caused by Nocardia brasiliensis

  • 1Department of Dermatology, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
  • 2Department of Laboratory Medicine, Dongguk University, Gyeongju, Korea.
  • 3Department of Pathology, College of Medicine, Dongguk University, Gyeongju, Korea.
  • 4Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.


Nocardiosis is an uncommon, potentially life-threatening infectious disease caused by several species of the genus Nocardia, which are Gram-positive branched bacilli. Most infections enter through the respiratory tract and then disseminate systemically but rarely has a primary infection occurred resulting from direct inoculation. Isolation of Nocardia from clinical specimens and identification of species is difficult and require a specialized microbiologist. We report a case of primary cutaneous nocardiosis caused by N. brasiliensis in a 68-year-old man who was diagnosed by bacterial culture and 16S ribosomal RNA sequencing. The skin lesions improved with trimethoprim- sulfamethoxazole antibiotic therapy for 6 months.


Cutaneous; Nocardia brasiliensis; Nocardiosis
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