Korean J Dermatol.  2007 Jul;45(7):735-738.

A Case of Annular Polycyclic Type of Subacute Cutaneous Lupus Erythematosus with Protein Losing Enteropathy

• Cho TH
• Cho HR
• Jeong KH
• Haw CR

Abstract

We present a case of annular polycylic type of subacute lupus erythematosus which fulfilled the criteria of systemic lupus erythematosus and was associated with protein losing enteropathy. A 37-year-old male had erythematous annular rashes with several painful, scattered ulcers and a generalized edematous appearance. Abnormal laboratory findings were hypoalbuminemia, low complement, positive Anti-Ro, La, and ANA in a speckled pattern. Tc-99m human serum albumin scintigraphy revealed extravasation within the small bowel. The histopathologic findings showed vacuolar degeneration, upper dermal edema and cleft with perivascular lymphocytic infiltration. Direct IF revealed granular deposition of IgG along the dermo-epidermal junction. The patient was treated with intravenous steroids and oral hydroxychloroquine.

Keyword

Annular type; Protein losing enteropathy; Subacute cutaneous Lupus erythematosus

MeSH Terms

Adult
Complement System Proteins
Edema
Exanthema
Humans
Hydroxychloroquine
Hypoalbuminemia
Immunoglobulin G
Lupus Erythematosus, Cutaneous*
Lupus Erythematosus, Systemic
Male
Protein-Losing Enteropathies*
Radionuclide Imaging
Serum Albumin
Steroids
Ulcer
Complement System Proteins
Hydroxychloroquine
Immunoglobulin G
Serum Albumin
Steroids