Korean J Dermatol.  2005 Nov;43(11):1544-1547.

A Case of Pigmented Purpuric Lichenoid Dermatitis of Gougerot-Blum Treated by Pentoxifylline

• Oh ST
• Yoon SY
• Lee SD
• Park HJ
• Lee JY
• Cho BK

Abstract

The pigmented purpuric lichenoid dermatitis of Gougerot-Blum is a subtype of the pigmented purpuric dermatoses characterized by small red-brown lichenoid papules that coalesce to form plaque lesions. This disorder usually persists for months to years and is resistant to conventional therapy. Pentoxifylline has been used to treat various dermatologic diseases, but its effectiveness in pigmented purpuric lichenoid dermatitis has not been reported. We tried oral pentoxifylline treatment, 400mg twice a day on a 63-year-old man with pigmented purpuric lichenoid dermatitis. A response was observed within 2 weeks. And after 8weeks, the skin lesion showed much improvement and therapy was discontinned. Four month later, he had a recurrence on the leg. He was treated again with pentoxifylline and after 3 weeks, the recurrent lesion showed resolution.

Keyword

Pigmented purpuric lichenoid dermatitis; Pentoxifylline

MeSH Terms

Dermatitis*
Humans
Leg
Middle Aged
Pentoxifylline*
Recurrence
Skin
Skin Diseases
Pentoxifylline