Korean J Dermatol.  1999 Feb;37(2):234-238.

Two Cases of Generalized Granuloma Annulare Controlled by Hydroxychloroquine

• Park JH
• Oh CK
• Jang HS
• Kwon KS
• Chung TA

Abstract

We report the clinical evolution of two male patients with generalized granulama annulare(GGA) who were controlled with hydroxychloroquine. In the first case, a 3-year-old boy was treated with systemic steroid, and in the second case, a 68-year-old man was treated with prednisolone, niacin, and retinoic acid. But, remission and recurrence of the skin lesions were repeated. A good clinieal response was achieved in both cases after administration of hydroxychloroquine without side effects or any signs of recurrence. Hydroxychloroquine may be helpful to treat the GGA that have side effects to the systemic corticosteroid or resistence to other therapeutic modalities.

Keyword

Generalized granulorna annulare; Hydroxychloroquine

MeSH Terms

Aged
Child, Preschool
Granuloma Annulare*
Granuloma*
Humans
Hydroxychloroquine*
Male
Niacin
Prednisolone
Recurrence
Skin
Tretinoin
Hydroxychloroquine
Niacin
Prednisolone
Tretinoin