Korean J Dermatol.  1997 Aug;35(4):819-823.

A Case of Multiple Histiocytomas in a Healthy Person

Affiliations
  • 1Department of Dermatology, Ewha Womans Univerisity School of Medicine, Seoul, Korea.

Abstract

Multiple histiocytomas are rare and defined when more than 15 lesions are present according to Baraf and Shapiro. It has been reported occurring in patients with autoimmune disease, who were receiving immunosuppressive treatment. Reports in the literature of these multiple lesions occurring in a healthy person are very rare. A 45-year-old man had 26 asymptomatic nodules on the trunk and upper extremities of two years duration. The lesions varied from 5mm to 2cm in size, were brownish, round, firm, nontender and positive for dimple signs. Microscopic examination of the lesions were indistinguish able from those seen in dermatofibroma. Most cells react intensively with factor XIIIa.

Keyword

Multiple histiocytomas; Healthy person

MeSH Terms

Autoimmune Diseases
Factor XIIIa
Histiocytoma*
Histiocytoma, Benign Fibrous
Humans
Middle Aged
Upper Extremity
Factor XIIIa
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