A Case of Verruciform Xanthoma Transformed from Lesions of Epidermal Nrvus Syndrome

Hur, Hoon; Jeong, Eui Chul; Choi, Kwang Ho; Kim, Jae Hoong; Kim, Joong Hwan; Lee, Kyung Soo

Abstract

We experienced a case of 16-year-old female with verruciform xanthoma transformed from lesions of epidermal nevus syndrome. The biopsy specimen of yellowish brown to red verrucous papule on the right buttock showed 1) uniform and verrucous acanthosis without cytological atypia, 2) parakeratosis and hyperkeratosis,3) variable foci of superficial necrosis with crusting and microabscess in the granular layer, 4) rete ridge elongation and papillomatosis, 5) characteristic foam cells located within the papillary dermis, but not below the rete ridges. Our case was diagnosed verruciform xanthoma by histopathologic finding which occured as a secondary development in lesions of epidermal nevus syndrome.