Korean J Gastrointest Endosc.
1998 Jun;18(3):392-397.
A Case of Cytomegalovirus Duodenitis Following an Allogenic Bone Marrow Transplantation
- Affiliations
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- 1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- 2Department of Diagnostic Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Abstract
- Cytomegalovirus(CMV) disease is one of the major causes of morbidity and mortality in immunocompromised patients, such as recipients of a solid organ or bone marrow allo-graft and patients with acquired immnune deficiency syndrome, CMV infection of the gastrointestinal tract may vary in location, extent, and clinical manifestation. As there is no pathognamonic endoscopic feature for CMV disease, a diagnosis of CMV infection has been made by confirming cytomegalic cells in mucosal specimens obtained from the gastrointestinal tract by an endoscopy. We repcet a case of a 38-year-old male patient with CMV duodenitis following an allogenic bone marrow transplantation(BMT), who had prolonged nausea and vomiting for 5 weeks after the BMT. He was diagnosed as having CMV duodenitis by identifying cytomegalic cells in duodenal mucosa biopsied by endoscopy and recovered after the treatment of ganciclovir.
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