Korean J Hematol.
2000 May;35(2):179-183.
Transient Myeloproliferative Disorder with Mosaic Down Syndrome: A Case Report
- Affiliations
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- 1Department of Pediatrics, Inje University College of Medicine, Pusan Paik Hospital, Pusan, Korea.
- 2Department of Clinical Pathology, Inje University College of Medicine, Pusan Paik Hospital, Pusan, Korea.
Abstract
- Individuals with Down syndrome have a high incidence of hematologic diseases such as transient myeloproliferative disorder (TMD) and acute leukemia comparing to the normal children. TMD usually undergoes complete recovery within a few months without any treatment. In Korea, there were several cases of TMD with Down syndrome in the literatures, but no reports of TMD in a phenotypically normal newborn with mosaic Down syndrome. We experienced a case of TMD in a 19- day-old male who was phenotypically normal newborn with mosaic Down syndrome. Specific treatment was withheld, hematologic recovery occurred within one month of diagnosis. We report the case with brief review of literature.
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