Korean J Hepatobiliary Pancreat Surg.  1997 Aug;1(2):143-149.

Pancreas Transplantation in DM

Affiliations
  • 1Department of Surgery, University of Ulsan College of Medicine & Asan Medical Center.

Abstract

Pancreas transplantation is primarily performed in type I juvenile onset diabetes mellitus(DM). At present the patients selected for transplantation often have complications such as end-stage renal disease, neuropathy and far advanced retinopathy. These days, the survival of pancreas transplantation for treatment of patients with type I DM has improved especially in simultaneous pancreas and renal transplantation. Various innovations in immunosuppression, management of the pancreatic exocrine secretion, recipient selection and HLA matching have contributed to achieving a reasonable outcome in pancreatic transplantation compared with other organ transplantations. Current improved graft survival has stimulated many centers in the world to become interested in pancreas transplantation program. We successfully performed the first case of simultaneous pancreas and kidney transplantation in our country in August 1992. Until now, 14 cases of pancreas transplantation have been performed in 3 centers, including our 12 cases.

Keyword

Pancreas; Transplantation; Type I DM

MeSH Terms

Diabetes Mellitus, Type 1
Graft Survival
Humans
Immunosuppression
Kidney Failure, Chronic
Kidney Transplantation
Organ Transplantation
Pancreas Transplantation*
Pancreas*
Transplantation
Transplants
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