Korean J Infect Dis.  1997 Jan;29(1):33-37.

Epidemiological Studies of Yersinia pseudotuberculosis Infection by Plasmid DNA Profile Assay

Affiliations
  • 1Department of clinical pathology, College of Medicine, Inje University, Seoul, Korea.
  • 2 Public Health Institute of Shimane Prefecture, Matsue, Japan.

Abstract

BACKGROUND: In order to investigate transmission route of Yersinia pseudotuberculosis infection in Korea, we tried epidemiological study among human strains, mountain spring water strain and wild mouse strain which were isolated in north eastern area of Seoul on spring in 1996.
METHODS
Plasmid profile (Restriction Endonuclease Analysis of Virulence Plasmid DNA analysis: REAP) assay in addition to serotyping were performed among human strains, mountain spring water strain and wild mouse strains.
RESULTS
All isolates were the same O serotype of 4b and the same REAP pattern of type D.
CONCLUSION
These results suggested that wild mice (especially Apodemus agrarius) were one of main reservoir of Y. pseudotuberculosis in Korea and their fecal material might contaminate mountain spring water. Most of human infections of Y. pseudotuberculosis were originated from drinking of contaminated mountain spring waters in Korea.

Keyword

Yersinia pseudotuberculosis; Epidemiology; Serotyping; Plasmid profile assay

MeSH Terms

Animals
DNA*
Drinking
Epidemiologic Studies*
Epidemiology
Humans
Korea
Mice
Murinae
Plasmids*
Seoul
Serotyping
Virulence
Yersinia pseudotuberculosis*
Yersinia*
DNA
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