Korean J Lab Med.
2002 Oct;22(5):364-366.
A Case of Agammaglobulinemia Detected by ABO Discrepancy in a 13-year-old Girl
- Affiliations
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- 1Department of Laboratory Medicine, Pusan National University College of Medicine, Busan, Korea. hhkim@pusan.ac.kr
- 2Department of Pediatrics, Pusan National University College of Medicine, Busan, Korea.
Abstract
- We report a case of agammaglobulinemia detected by ABO discrepancy in a 13-year-old girl. At first, she visited Pusan National University Hospital complaining of joint swelling and pain. For trans-fusion, the ABO blood grouping was done. The cell typing was B, but anti-A was not found in the serum with repeated testing. Then, serum protein electrophoresis, immunoelectrophoresis and immunoglob-ulin quantitation showed a markedly decreased level in gamma-globulin. B lymphocyte was less than 1% of peripheral lymphocytes. There were no remarkable abnormal findings in the clinical and laboratory results of her parents. The patient represented an apparent agammaglobulinemia without clinically significant infection for three months. Further follow-up is needed to evaluate the patient.
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