Korean J Med.
2009 Apr;76(Suppl 1):S204-S207.
Meningitis following vaccination with yellow-fever vaccine
- Affiliations
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- 1Department of Infectious Disease, Keimyung University School of Medicine, Daegue, Korea. 121rsy@dsmc.or.kr
- 2Division of Arboviruses, Center for Immunology and Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Seoul, Korea.
- 3Department of Laboratory Medicine, Keimyung University School of Medicine, Daegue, Korea.
Abstract
- Yellow fever is the original viral hemorrhagic fever (VHF), a pansystemic viral sepsis with viremia, fever, prostration, hepatic, renal, and myocardial injury, hemorrhage, shock, and high lethality. Yellow fever was one of the most feared lethal diseases before the development of an effective vaccine. Yellow fever (YF) can be prevented by an attenuated vaccine. The yellow-fever 17D vaccine developed in the 1930s has been regarded as one of the most successful live attenuated vaccines, with few side effects or adverse events. The adverse effects associated with yellow-fever vaccine are generally mild and include headache, myalgia, and low-grade fever. Recently, however, some cases of severe neurologic disease and multi-organ system disease have been described in individuals who received yellow-fever vaccine. We report the case of a 39-year-old female with meningitis following vaccination with 17D yellow-fever vaccine.
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