Korean J Obstet Gynecol.  2007 Oct;50(10):1414-1421.

A case of sarcoma arising in ovarian mature cystic teratoma

• Park MS
• Suh MJ
• Choi JH
• Yoon JH
• Park DC

Abstract

Benign cystic teratoma is the common ovarian tumor, and the incidence reported about 20%. Between 1 and 2% of mature cystic teratomas undergo malignant trasformation. This occurs most frequently in postmenopausal women, who account for only 10% of mature cystic teratomas. Among the malignant transformations, squamous cell carcinoma is the most common type (over 75%), and adenocarcinoma, undifferentiated carcinoma, malignant melanoma, thyroid adenocarcinoma, and sarcoma have been reported in the literature. Because of its rarity, the clinico-pathologic characteristics are not well established, and there is no consensus on optimal therapy. There is also no consensus regarding the efficacy of postoperative therapy. We experienced a case of sarcoma of the ovary arising in mature cystic teratoma, which is presented with a brief review of literature.

Keyword

Ovarian sarcoma; Mature cystic teratoma; Malignant transformation

MeSH Terms

Adenocarcinoma
Carcinoma
Carcinoma, Squamous Cell
Consensus
Female
Humans
Incidence
Melanoma
Ovary
Sarcoma*
Teratoma*
Thyroid Gland