Korean J Obstet Gynecol.  2003 Oct;46(10):1943-1949.

The Significance of the Antral Follicle Number Prior to Stimulation in Predicting the Outcome of Assisted Reproductive Technologies

• Jo KM
• Jung NH
• Chung SE
• Jung US
• Kim T
• Kim SH

Abstract

BACKGROUND: Recruitment and development of multiple follicles in response to gonadotropin stimulation are the key factors leading to successful treatment by assisted reproductive technologies. Prediction of ovarian responses prior to stimulation is useful in counselling and helpful in adjusting the dosage of gonadotropin to individual patients.
OBJECTIVE
To evaluate the number of antral follicles of both ovaries as a predictor of outcome of assisted reproductive technologies.
METHODS
Data were collected by a retrospective analysis. A total of 56 consecutive infertile women were undergoing the first cycle using a standard regimen of ovarian stimulation from July, 2000 to June, 2001. Basal FSH, LH, prolactin, and estradiol concentration were measured. The number of follicles (2-5 mm) were recorded.
RESULTS
In women with fewer antral follicles, the number of retrieved eggs was significantly decreased and increased the duration and dosage of human menopausal gonadotropin, but pregnancy rate was similar to those with a higher number of antral follicles.
CONCLUSION
It is suggested that the total antral follicle number is sensitive ultrasound parameter in predicting the ovarian response.

Keyword

Antral follicle; Ovarian reserve; Assisted reproductive technologies

MeSH Terms

Eggs
Estradiol
Female
Gonadotropins
Humans
Ovary
Ovulation Induction
Ovum
Pregnancy Rate
Prolactin
Reproductive Techniques, Assisted*
Retrospective Studies
Ultrasonography
Estradiol
Gonadotropins
Prolactin