Korean J Occup Environ Med.  1994 Sep;6(2):402-410.

Cholinesterase activity and Pestieide Compounds in Blood of Pestieide Sprayers

Affiliations
  • 1Department of Preventive Medicine and Public Health, Yonsei University College of Medicine, Korea.
  • 2Doping Control Center, Korea Institute of Science and Technology, Korea.

Abstract

In order to ascertain the status of health damage among Korean farmers who spray pesticides regularly in summer, blood and urine samples were collected for 88 volunteers during July to Septembei in 1990. Serum cholinesterase activity, parent compounds of pesticides in blood and urine, SGOT, SGPT, blood pressure, pulse rate were measured. The results were as follows ; 1. Mean cholinesterase activity after spraying pesticides was significantly lower than that before splaying. While proportion of abnormal cholinesterase activity (<1900U/L) group was 2.3% before spraying pesticides, tHe proportion of the group after spraying was 22.8% 2. Cholinesterase activity were decreased over 50% in 14.7% of the suhjects who can be classified into poisoning group 3. While pulse rate and blood pressure were slightly increased in poisoning group, those were significantly decreased in non-poisoning group. 4. Consecutive splaying of pesticide caused further reduction of cholinesterase activity, 5. Five parent compounds of pesticides frequently used during summer farming were analyzed using 106 blood samples. IBP in one sample and Isoprothiolane in four samples were detected. No parent compounds were detected in urine samples.

Keyword

Pesticides sprayer; Health damage; Cholinesterase

MeSH Terms

Alanine Transaminase
Aspartate Aminotransferases
Blood Pressure
Cholinesterases*
Heart Rate
Humans
Parents
Pesticides
Poisoning
Volunteers
Alanine Transaminase
Aspartate Aminotransferases
Cholinesterases
Pesticides
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