Korean J Perinatol.
1999 Dec;10(4):518-523.
Three Cases of Holoprosencephaly
Abstract
- Holoprosencephaly is a rare complex cerebral anomaly produced by a failure of cleavage of the prosencephalon. The association of brain anomalies and facial dysmorphism is a typical finding. There are three types(alobar, semilobar, and lobar) of holoprosencephaly. Among these the alobar type has the worst prognosis. The early antenatal diagnosis of the holoprosencephaly is very important determinant for initiating the therapeutic abortion. We report 3 cases of alobar holoprosencephaly with the brief review of the literature.
