Korean J Thorac Cardiovasc Surg.  1998 Nov;31(11):1102-1105.

Lobectomy in Pulmonary Infections in Chronic Granulomatous Disease of Childhood: A Case Report

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Ewha Womans University, Tongdaemoon Hospital, Korea.

Abstract

Chronic granulomatous disease in childhood is a rare inheritable disorder of phagocytic cells in which defective production of the reactive intermediates of oxygen predisposes the patient to severe recuring pyogenic infections. The lung is the most common site of infection and pulmonary disease is the primary cause of death for greater than 50% of children with chronic granulomatous disease. Although the role of surgery in management of this disease remains undefined, rapid diagnosis of the underlying pulmonary problem is crucial to determine the most appropriate antimicrobial therapy and surgical techniques such as lobectomy of involved areas lead to more rapid recovery and thus allow the antibiotics to be more efficacious in these cases. We have treated a one month old male baby who had the chronic granulomatous disease with pulmonary infection. Wide surgical resection of the affected lobe and use of antibiotics and antifungals were carried out with good clinical results. He was well after the operation.

Keyword

Granulomatous Disease; Chronic; Lobectomy

MeSH Terms

Anti-Bacterial Agents
Cause of Death
Child
Diagnosis
Granulomatous Disease, Chronic*
Humans
Lung
Lung Diseases
Male
Oxygen
Phagocytes
Anti-Bacterial Agents
Oxygen
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