J Clin Pathol Qual Control.  1999 Jun;21(1):147-158.

Annual Report on External Quality Assessment in Diagnostic Gentics in Korea (1998)

Affiliations
  • 1Diagnostic Genetics Subcommittee, The Korean Association of Quality Assurance for Clinical Pathology, Seoul, Korea.

Abstract

The importance of quality control for dramatically growing genetic tests continues to be emphasized with increasing clinical demands. Diagnostic genetics subcommittee of KSQACP performed one proficiency trial for molecular genetic tests and two trials for cytogenetic study in 1998. The first trial for molecular studies included genetic tests for genetic disorders (DMD/BMD, Apo E genotyping), hematologic malignancies and infectious diseases (tuberculosis and hepatitis C). The trial materials for molecular tests were distributed to 39 laboratories and most of them performed acceptable. Only small number of laboratories revealed some problems in prevention of contamination for PCR tests. Two trials for cytogenetics were performed in 29 laboratories and answered correctly in most laboratories except some errors in nomenclature and problems in analysis for hematologic malignancies. It was concluded that external quality assessment program for diagnostic genetics could be helpful to improve the quality of genetic laboratory by continuous education and good quality control materials.


MeSH Terms

Apolipoproteins E
Communicable Diseases
Cytogenetics
Education
Genetics
Hematologic Neoplasms
Hepatitis
Korea*
Molecular Biology
Polymerase Chain Reaction
Quality Control
Apolipoproteins E
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