Nucl Med Mol Imaging.  2010 Apr;44(1):87-89.

Radiography, Bone Scan, and F-18 FDG PET/CT Imaging Findings in a Patient with Paget's Disease

Affiliations
  • 1Department of Radiology, Korea University Guro Hospital, Seoul, Korea
  • 2Department of Nuclear Medicine, Korea University Guro Hospital, College of Medicine, 80 Guro-Dong, Guro-Gu, Seoul 152-050, Korea. seiong@korea.ac.kr

Abstract

BACKGROUND
A 52-year-old female patient sought evaluation at our hospital for an incidental abnormal finding on an abdominal radiograph.
METHODS
The initial radiograph showed irregular sclerotic changes involving the right pelvic bone. At the same time, bone scintigraphy showed intense hot uptake in the right iliac and pubic bones. CT images showed characteristic thickening of the pelvic brim, suggesting the mixed phase of Paget's disease.
RESULTS
The level of alkaline phosphatase (ALP) was 266 IU/l. 18F-FDG PET/CT images also showed diffusely increased 18F-FDG uptake in the right pelvic bone. However, the findings of 18F-FDG PET/CT were less notable than those of bone scintigraphy.
CONCLUSION
We report the imaging findings of a patient with Paget's disease evaluated by radiography, bone scintigraphy, and 18F-FDG PET/CT.

Keyword

Paget's disease; 18F-FDG PET/CT; Bone scintigraphy

MeSH Terms

Alkaline Phosphatase
Female
Fluorodeoxyglucose F18
Humans
Middle Aged
Pelvic Bones
Pubic Bone
Alkaline Phosphatase
Fluorodeoxyglucose F18
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