Clin Pediatr Hematol Oncol.
2012 Oct;19(2):128-131.
A Adrenocortical Oncocytoma in a 10-year-old Girl Presenting with Virilization
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Inje University, Busan, Korea. pjk4285@hanmail.net
- 2Department of Patholgy, College of Medicine, Inje University, Busan, Korea.
- 3Department of Surgery, College of Medicine, Inje University, Busan, Korea.
Abstract
- Adrenocortical oncocytoma is a rare epithelial tumor only described in adults and in most cases, benign and non-functioning. Histologically characterized by cells with eosinophilic granular cytoplasm and ultra-structurally by the presence of numerous closely packed mitochondria. We report a case of adrenal oncocytoma developed in a 10-year-old girl who presented a left adrenal mass with low voice tone, excessive hair growth, and elevation of the plasma testosterone and dehydroepiandrosterone sulfate levels as a result of overproduction of adrenal steroid hormones. After the left adrenalectomy, her hormone levels were normalized.
