Clin Pediatr Hematol Oncol.  2012 Oct;19(2):123-127.

A Case Report of Botryoid Wilms Tumor: Has Different Clinical Manifestations

Affiliations
  • 1Department of Pediatrics, Kyungpook National University College of Medicine, Daegu, Korea. kslee@knu.ac.kr
  • 2Department of Pediatric Surgery, Kyungpook National University College of Medicine, Daegu, Korea.
  • 3Department of Pathology, Kyungpook National University College of Medicine, Daegu, Korea.

Abstract

A previously healthy, 16-month-old boy was admitted to hospital due to fever, vomiting, and persistent gross hematuria for 2 weeks. His imaging studies showed an inhomogeneous mass, in a left dilated renal pelvis and proximal ureter, which was suggestive of a kidney neoplasm. A stage I Wilms tumor limited to the nephrectomised kidney was diagnosed by histology. The margin of ureter and renal vessels were clear. There was no evidence of anaplasia, angiolymphatic invasion, or skeletal muscle differentiation. In addition, there were polypoid protrusions of tumor into the pelvicaliceal system, resulting in such a 'botryoid' appearance. The patient had been treated with adjuvant chemotherapy using 7 cycles of intravenous actinomycin-D and vincristine (NWTS regimen EE4A) for 5 months. During a 22-month follow-up period, there has been no evidence of tumor recurrence.

Keyword

Wilms tumor; Botryoid; Hematuria

MeSH Terms

Anaplasia
Chemotherapy, Adjuvant
Fever
Follow-Up Studies
Hematuria
Humans
Infant
Kidney
Kidney Neoplasms
Kidney Pelvis
Muscle, Skeletal
Recurrence
Ureter
Vincristine
Vomiting
Wilms Tumor
Vincristine
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