Clin Exp Reprod Med.  2014 Dec;41(4):151-157. 10.5653/cerm.2014.41.4.151.

Association of the neutrophil-to-lymphocyte ratio and CA 125 with the endometriosis score

• Kim SK
• Park JY
• Jee BC
• Suh CS
• Kim SH

• KMID: 2049073
• DOI: http://doi.org/10.5653/cerm.2014.41.4.151

Abstract

OBJECTIVE
To evaluate the association between the severity of endometriosis and the preoperative neutrophil-to-lymphocyte ratio (NLR) and serum level of cancer antigen 125 (CA 125).
METHODS
Data were obtained from the medical records of 419 patients who underwent laparoscopic conservative surgery for ovarian endometrioma between April 2005 and March 2013. Each patient's preoperative complete blood count was recorded and the endometriosis score was assessed.
RESULTS
The endometriosis score was not associated with either the NLR or the serum level of CA 125. The endometriosis score was negatively related to preoperative hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. The only positive association was between NLR and the patients' age. NLR and preoperative serum anti-Mullerian hormone level were found to be negatively related.
CONCLUSION
The severity of endometriosis was not associated with the serum level of CA 125 or the NLR. The presence of a negative correlation between the severity of endometriosis and red blood cell dynamics needs further investigation.

Keyword

Blood cell count; CA-125 antigen; Endometriosis; Hemoglobins; Lymphocytes; Neutrophils

MeSH Terms

Anti-Mullerian Hormone
Blood Cell Count
CA-125 Antigen
Endometriosis*
Erythrocyte Indices
Erythrocytes
Female
Hematocrit
Humans
Lymphocytes
Medical Records
Neutrophils
Anti-Mullerian Hormone
CA-125 Antigen