Clin Endosc.  2012 Jun;45(2):165-168. 10.5946/ce.2012.45.2.165.

A Case of Giant Lipoma Causing Chronic Recurrent Intussusception of the Colon

  • 1Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
  • 2Department of Pathology, Hallym University College of Medicine, Chuncheon, Korea.


Colonic lipomas, which often occur in elderly women, usually have small size and occur mainly in the cecum and ascending colon. Most colonic lipomas are asymptomatic and identified incidentally at the time of endoscopy or surgery. However, they may cause symptoms such as bleeding, obstruction or intussusception as their size increases. Intermittent episodes of intussusception are uncommon but may be caused by large pedunculated lipoma. In a 68-year-old woman suffering intermittent abdominal pain, 5.5x4.5x3.8-cm huge mass was found by colonoscopy at proximal ascending colon, which was intussuscepted to proximal transverse colon on abdominal computed tomography. Segmental right colonic resection was conducted. We report a case of symptomatic giant pedunculated colonic lipoma causing intussusception requiring surgical intervention, with a successful recovery after surgery.


Intussusception; Colon; Lipoma

MeSH Terms

Abdominal Pain
Colon, Ascending
Colon, Transverse
Stress, Psychological


  • Fig. 1 Colonoscopic findings. (A) Huge, round, hyperemic mass covered with superficial ulcer is observed at proximal ascending colon. On the center of ulcer, the exposed vessels are seen. (B) It shows another small ulcer near the base of the mass, and inflammated hyperemic mucosa is seen on the body of the mass.

  • Fig. 2 Abdominal computed tomography findings. (A) It shows a concentric multi-layered mass at the proximal A-colon, which extended to proximal T-colon, and 6×4 cm sized well defined low density mass in proximal T-colon, suggesting colo-colic intussusception caused by lipoma. (B) In the coronal images, introcession from the cecum and shortened A-colon are seen.

  • Fig. 3 Gross findings. (A) The polypoid submucosal mass is identified in the cecum. (B) The mass is confined to the submucosa, and the cut surface appears bright yellow and soft.

  • Fig. 4 Pathologic finding. The tumor consists of the mature adipocytes with focal fat necrosis, supporting the lipoma (H&E stain, ×100).


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