Clin Endosc.  2012 Mar;45(1):11-24. 10.5946/ce.2012.45.1.11.

Korean Guideline for Colonoscopic Polypectomy

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
  • 2Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea.
  • 3Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea. diksmc.park@samsung.com
  • 4Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
  • 5Department of Radiology, Konkuk University School of Medicine, Seoul, Korea.
  • 6Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
  • 7Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 8Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
  • 9Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
  • 10Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
  • 11Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 12Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
  • 13Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Abstract

There is indirect evidence to suggest that 80% of colorectal cancers (CRC) develop from adenomatous polyps and that, on average, it takes 10 years for a small polyp to transform into invasive CRC. In multiple cohort studies, colonoscopic polypectomy has been shown to significantly reduce the expected incidence of CRC by 76% to 90%. Colonoscopic polypectomy is performed frequently in primary outpatient clinics and secondary and tertiary medical centers in Korea. However, there are no evidence-based, procedural guidelines for the appropriate performance of this procedure, including the technical aspects. For the guideline presented here, PubMed, Medline, and Cochrane Library literature searches were performed. When little or no data from well-designed prospective trials were available, an emphasis was placed on the results from large series and reports from recognized experts. Thus, these guidelines for colonoscopic polypectomy are based on a critical review of the available data as well as expert consensus. Further controlled clinical studies are needed to clarify aspects of this statement, and revision may be necessary as new data become available. This guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients. This guideline is not a rule and should not be construed as a legal standard of care or as encouraging, advocating, requiring, or discouraging any particular treatment. Clinical decisions for any particular case involve a complex analysis of the patient's condition and the available courses of action.

Keyword

Colonoscopy; Polypectomy; Guideline

MeSH Terms

Adenomatous Polyps
Ambulatory Care Facilities
Cohort Studies
Colonoscopy
Colorectal Neoplasms
Consensus
Humans
Incidence
Korea
Polyps
Standard of Care

Figure

  • Fig. 1 Efficacy of prophylactic saline with epinephrine injection prior to snare polypectomy for the prevention of overall bleeding (early and late). CI, confidence interval.

  • Fig. 2 Efficacy of prophylactic saline with epinephrine injection prior to snare polypectomy for the prevention of early bleeding. CI, confidence interval.

  • Fig. 3 Efficacy of prophylactic saline with epinephrine injection prior to snare polypectomy for the prevention of late bleeding. CI, confidence interval.

  • Fig. 4 Efficacy of the prophylactic method (endoloop or clip application) for the prevention of early bleeding in cases with large pedunculated polyps. CI, confidence interval.

  • Fig. 5 Efficacy of the prophylactic method (endoloop or clip application) for the prevention of delayed bleeding in cases with large pedunculated polyps. CI, confidence interval.

  • Fig. 6 Subgroup analysis of prophylactic methods versus submucosal injections for the prevention of early bleeding. CI, confidence interval.

  • Fig. 7 Subgroup analysis of prophylactic methods versus submucosal injections for the prevention of delayed bleeding. CI, confidence interval.

  • Fig. 8 Subgroup analysis of the prophylactic method versus no injection for the prevention of early bleeding. CI, confidence interval.

  • Fig. 9 Subgroup analysis of the prophylactic method versus no injection for the prevention of delayed bleeding. CI, confidence interval.

  • Fig. 10 Efficacy of the prophylactic method (argon plasma coagulation or clip application) for the prevention of delayed bleeding. CI, confidence interval.


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