Ann Surg Treat Res.  2015 Jul;89(1):51-54. 10.4174/astr.2015.89.1.51.

Use of cryopreserved cadaveric arterial allograft as a vascular conduit for peripheral arterial graft infection

Affiliations
  • 1Gachon University of Medicine and Science, Incheon, Korea.
  • 2Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ypcho@amc.seoul.kr
  • 3Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • 4Department of Surgery, Ulsan University Hospital, Ulsan, Korea.

Abstract

Major peripheral arterial graft infection is a potentially devastating complication of vascular surgery, associated with significant mortality and high amputation rates. Autologous saphenous veins are considered optimal arterial conduits for lower extremity revascularization in infected fields, but they are often unavailable or unsuitable in these patients. This study describes two patients with major peripheral graft infection, but without available autologous veins, who underwent graft excision and cryopreserved cadaveric arterial allograft reconstruction. Although long-term graft durability is unclear because of gradual deterioration and degeneration, these findings suggest that cadaveric allografts may be good options for patients with major peripheral graft infection.

Keyword

Blood vessel prosthesis; Infection; Tissue preservation; Cadaver; Allografts

MeSH Terms

Allografts*
Amputation
Blood Vessel Prosthesis
Cadaver*
Humans
Lower Extremity
Mortality
Saphenous Vein
Tissue Preservation
Transplants*
Veins
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