Infect Chemother.  2012 Aug;44(4):319-322. 10.3947/ic.2012.44.4.319.

Erythema Elevatum Diutinum in Human Immunodeficiency Virus Infected Patient

Affiliations
  • 1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. amoxj@yonsei.ac.kr
  • 2Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 3Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.

Abstract

Erythema elevatum diutinum (EED) is emerging as a specific HIV-associated dermatosis which can be easily misdiagnosed as Kaposi's sarcoma or bacillary angiomatosis. Until now, no case of HIV-associated EED had been reported in Korea. We report a case of EED in a 49-year-old man with HIV infection. The patient was diagnosed with HIV-infection and treated with a combination of anti-retroviral agents and dapsone. Two years after the start of treatment the lesion had regressed.

Keyword

Erythema elevatum diutinum; Human immunodeficiency virus; Antiretroviral therapy; Highly active; Dapsone

MeSH Terms

Angiomatosis, Bacillary
Anti-Retroviral Agents
Dapsone
Erythema
HIV
HIV Infections
Humans
Korea
Middle Aged
Sarcoma, Kaposi
Skin Diseases
Vasculitis, Leukocytoclastic, Cutaneous
Anti-Retroviral Agents
Dapsone
Vasculitis, Leukocytoclastic, Cutaneous

Figure

  • Figure 1 (A) Multiple variably sized light brown colored hard nodules on the left ankle. (B) Erythematous elevatum diutinum is regressed after 2-years of treatment with HAART and dapsone.

  • Figure 2 Histopathologic finding shows perivascular mixed inflammatory cell infiltration composed predominantly of neutrophils with a few eosinophils, significant karyorrhectic debris and fibrin depositions (H&E stain, ×200).


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