Korean J Anesthesiol.  2007 Sep;53(3):407-410. 10.4097/kjae.2007.53.3.407.

Anesthetic Management of a Patient with Glanzmann's Thrombasthenia: A case report

  • 1Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.
  • 2Department of Dental Anesthesiology, Seoul National University Dental Hospital, Seoul, Korea. dentane@snu.ac.kr
  • 3Department of Dental Anesthesiology, Seoul National University School of Dentistry, Seoul, Korea.


Glanzmann's thrombasthenia is a rare autosomal recessive disorder characterized by bleeding tendency due to decreased coagulation function of platelets. Perioperative adequate blood transfusion including preoperative platelet transfusion seems to be the most important component affecting anesthetic management. Also, minimally invasive techniques should be used at the time of induction of anesthesia and the use of recombinant activated coagulation factor VII may be considered. We successfully conducted an anesthetic management for dental procedure in a four-year-old child with Glanzmann's thrombasthenia using preoperative platelet transfusion. Thus we present this anesthetic experience and share informations on anesthetic management of patients with Glanzmann's thrombasthenia.


dental procedure; Glanzmann thrombasthenia; platelet transfusion
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