Korean J Blood Transfus.
2003 Dec;14(2):240-245.
Two Cases of ABO Discrepancy due to Hypogammaglobulinemia
- Affiliations
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- 1Department of Laboratory Medicine, Kangwon National University College of Medicine, Chuncheon, Korea.
- 2Department of Internal Medicine, Kangwon National University College of Medicine, Chuncheon, Korea.
- 3Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Korea.
- 4Department of Anatomy, Korea University College of Medicine, Seoul, Korea.
Abstract
- Two cases of ABO discrepancy were observed in thirty-year old woman with gall bladder abscess and fifty-five-year old woman with hepatocellular carcinoma. Their red cells were typed as group O and their serum had only anti-A antibody. Absence of A and B antigens on their RBCs were confirmed by adsorption elution test and saliva test. The B transferase activities were not demonstrated in their serum. Their ABO genotypes were O/O by sequence specific polymerase chain reaction. Their serum protein electrophoresis showed hypogammaglobulinemia pattern, and immunoglobulin levels (IgG, IgA, IgM) were decreased (39 mg/dL, 46 mg/dL, <5 mg/dL and 63 mg/dL, 65 mg/dL, 12 mg/dL, respectively).
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