Korean J Oral Maxillofac Radiol.  2007 Dec;37(4):225-230.

Three cases of cholesterol granuloma in the mandible

Affiliations
  • 1Department of Oral and Maxillofacial Radiology, School of Dentistry, Seoul National University, Seoul, Korea.
  • 2Department of Oral and Maxillofacial Surgery, Sanggye Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
  • 3Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
  • 4Department of Oral and Maxillofacial Radiology, Dental Research Institute and BK 21, School of Dentistry, Seoul National University, Seoul, Korea. raychoi@snu.ac.kr

Abstract

Cholesterol granuloma is an unusual clinical entity described as an inflammatory granulation in response to the deposit of cholesterol crystals. It can develop in any portion of air cells within the temporal bone as a result of a lack of aeration and inadequate drainage, especially in the middle ear cavity. Here, we report very unusual three cases of cholesterol granuloma developed in mandible. In the first case a 68-year-old male with a large mass arising from the mandible was observed. Panoramic radiograph and computed tomography scans revealed a huge expanding lesion in the mandible. In the second case a 47-year-old female with a cystic lesion in the mandible was observed. And in the third case a 19-year-old male complaining atypical facial pain had a large lesion in the mandibular ramus. The histopathologic examinations of the cases showed numerous cholesterol crystals surrounded by ultinucleated foreign body giant cells.

Keyword

Cholesterol Granuloma; Mandible; Diagnostic Imaging

MeSH Terms

Aged
Cholesterol*
Diagnostic Imaging
Drainage
Ear, Middle
Facial Pain
Female
Giant Cells, Foreign-Body
Granuloma*
Humans
Male
Mandible*
Middle Aged
Temporal Bone
Young Adult
Cholesterol
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