J Korean Radiol Soc.  2000 Feb;42(2):341-347. 10.3348/jkrs.2000.42.2.341.

MRI Findings of Malignat Lymphoma Presenting in Bones

Affiliations
  • 1Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Diagnostic Radiology, Pundang CHA General Hospital, Pochon CHA University College of Medicine, Korea.

Abstract

PURPOSE: To analyze the MR finding of skeletal malignant lymphoma. MATERIALS AND METHODS: The authors retrospectively reviewed the MR imaging findings(location, signal intensity and contrast enhancement of lesions, and patterns of bone marrow involvement) of 12 patients with malignant lymphoma presenting in bones and confirmed by incisional biopsy, blind bone marrow biopsy or fol-low-up MR imaging. RESULTS: Among the 15 lesions in 12 patients, the spine was the most commonly involved site(n=5), followed by the ilium(n=4), femur(n=3), sternum(n=2), and tibia(n=1). On T1-weighted images, lesions showed signal intensity close to muscle, while on T2-weighted images, involved bones showed variable signal intensity from muscle to water signal intensity. Patterns of bone marrow involvement were nodular(n=2), diffuse(n=5), or segmental(n=8). All cases of segmental bone marrow involvement also produced soft tissue mass. In two cases in which this occurred, cortical breakdown was not noted. CONCLUSION: On T1- and T2-weighted MR images, particularly the latter, bone marrow involvement of malignant lymphoma was observed, with variable signal intensity. Contrast enhanced images revealed distinct lesion. Patterns of bone marrow involvement varied.

Keyword

Bone neoplasms; Lymphoma; Bones, MR

MeSH Terms

Biopsy
Bone Marrow
Bone Neoplasms
Humans
Lymphoma*
Magnetic Resonance Imaging*
Retrospective Studies
Spine
Water
Water
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