J Korean Radiol Soc.  2008 Jun;58(6):591-598. 10.3348/jkrs.2008.58.6.591.

Small Focal Hepatic Lesions <=1 cm: Their Detection and Characterization with Performing Diffusion-Weighted Sensitivity-Encoding versus SPIO-Enhanced 3T MR Imaging

Affiliations
  • 1Department of Radiology, Konyang University Hospital, Korea. bookdoo7@chollian.net
  • 2Department of Gastroenterology, Konyang University Hospital, Korea.

Abstract

PURPOSE
We wanted to compare the accuracy of 3T DW-SENSE imaging with that of SPIO-enhanced imaging for the detection and characterization of small hepatic lesions.
MATERIALS AND METHODS
124 focal hepatic lesions of 42 patients were retrospectively reviewed. The DW-SENSE imaging and four T2-weighted imaging, including the respiratory-triggered and breath-hold fast spin-echo images, the half-fourier single-shot turbo spin-echo images and the T2*-weighted fast field-echo images, were acquired. Four T2-weighted examinations were performed after administering SPIO. The images were divided into two sets: the SPIO image set (four pre- and post-contrast T2-weighted images) and the DW-SENSE image set (four DW-SENSE and pre-contrast T2-weighted images). These were sorted according to the confidence levels for lesion detection and characterization into four and five grades. The ROC curve (Az) was calculated.
RESULTS
The detection accuracy with using the DW-SENSE image set (Az=0.932, 0.889) was higher than with using the SPIO image set (Az=0.852, 0.798) for all the lesions and the small lesions (<= 1 cm) (p < 0.05). For lesion characterization, the accuracy with using the DW-SENSE image set (Az=0.934, 0.896) was higher than that with using the SPIO image set (Az=0.914, 0.882) for all the lesions and the small lesion, but this was not statistically significant.
CONCLUSION
The 3T MR DW-SENSE image set showed higher accuracy for the detection of small hepatic lesions than the SPIO image set.

Keyword

Liver; Magnetic resonance (MR); Diffusion magnetic resonance imaging; Contrast media

MeSH Terms

Contrast Media
Diffusion Magnetic Resonance Imaging
Humans
Liver
Retrospective Studies
ROC Curve
Contrast Media
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