J Korean Ophthalmol Soc.  2007 Jul;48(7):911-918.

Long-term Results of Vision and Fundus Findings in X-linked Juvenile Retinoschisis

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ysyu@snu.ac.kr
  • 2Seoul National University Boramae Hospital, Seoul, Korea.
  • 3Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.

Abstract

PURPOSE: To evaluate long-term changes in visual acuity, fundus findings and complications in X-linked juvenile retinoschisis.
METHODS
A retrospective chart review was conducted on 48 patients diagnosed with X-linked juvenile retinoschisis and followed for a minimum of 12 months.
RESULTS
Forty-eight males (mean age 5.7 years) were followed for a mean of 6.3 years. The mean visual acuities were 0.14 at the initial and most recent examinations without significant change (p=0.67). Macular abnormalities were seen in all eyes. Macular lesions varied as follows: decreased foveal reflex (12.5%), typical foveal schisis (77.1%), atrophic change (5.2%), and macula-involving peripheral schisis (5.2%). When patients had different macular findings, the mean visual acuities were significantly different among groups (p< or =0.005), except those between the atrophic change group and the macula-involving peripheral schisis group. Peripheral schisis was detected in 66% of patients. The fundus findings were stationary during the follow-up period except in complicated cases with vitreous hemorrhage (15.6%).
CONCLUSIONS
X-linked juvenile retinoschisis causes bilateral visual acuity loss, affecting maculae. In uncomplicated cases, changes in visual acuity and fundus findings were not significant during the follow-up period.

Keyword

Fundus findings; Visual acuity; X-linked juvenile retinoschisis

MeSH Terms

Follow-Up Studies
Humans
Male
Reflex
Retinoschisis*
Retrospective Studies
Visual Acuity
Vitreous Hemorrhage
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