Korean J Gastrointest Endosc.  2005 Feb;30(2):99-102.

A Case of Malakoplakia Treated by Antibiotics in the Rectum

Affiliations
  • 1Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. gasong@pusan.ac.kr

Abstract

Malakoplakia is a rare chronic inflammatory process, most commonly affecting the urinary tract. This entity was first described by Michaelis and Gutman in 1902. As of 1995, only 85 cases of malakoplakia of the gastrointestinal tract has been reported. The common sites of colonic involvement are the rectum, sigmoid, and right colon, in descending order of frequency. The most common disease associated with malakoplakia is colorectal carcinoma. Surgical resection is the treatement of choice for cases associated with carcinoma or complications. But in other cases, medical treatment could be attempted. Antimicrobial drugs, such as trimethoprime-sufamethoxazole, rifampin, or as recently suggested, ciprofloxacin can be used. We report a case of rectal malakoplakia treated by ciprofloxacin with a review of literatures.

Keyword

Malakoplakia; Ciprofloxacin; Rectum

MeSH Terms

Anti-Bacterial Agents*
Ciprofloxacin
Colon
Colon, Sigmoid
Colorectal Neoplasms
Gastrointestinal Tract
Malacoplakia*
Rectum*
Rifampin
Urinary Tract
Anti-Bacterial Agents
Ciprofloxacin
Rifampin
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