Korean J Dermatol.  2007 Jan;45(1):9-13.

Clinical Study of the Results of Patch Test in Patients with Eczematous Cheilitis

Affiliations
  • 1Department of Dermatology, Gachon University of Medicine and Science, Incheon, Korea. dmjj1@gilhospital.com
  • 2Department of Dermatology, College of Medicine, Inha University, Incheon, Korea.

Abstract

BACKGROUND: Cheilitis is a common problem, the cause of which is often obscure.
OBJECTIVE
We evaluated the frequency of allergic contact cheilitis and irritant contact cheilitis among 23 eczematous cheilitis patients via patch testing and assessment of past medical history.
METHODS
This study consisted of 23 patients with eczematous cheilitis who had visited the Department of Dermatology, two University Hospital in Incheon, between January 2005 and August 2006. Of the 23 patients, 20 were female, and the age range was 15 to 70 years. We analyzed the clinical characteristics (age, gender, duration, atopic or allergic disease, lip licking) of the patients. All patients were patch-tested with the Korean standard series, 9 patients with the Cosmetic series and 5 patients with as is test. We then analyzed the results of the patch tests and evaluated the relevance of any positive results.
RESULTS
Of the cases, 34.78% were identified as irritant contact dermatitis (ICD), and 30.43% as allergic contact dermatitis (ACD). Furthermore, of the 23 patients, 11 were positive to one or more antigen and 7 of these had a clinical relevance for positive antigen. The substances causing a positive reaction, triggering ACD were identified as medicaments applied to the lip, lipstick ingredients and toothpaste.
CONCLUSION
The most common cause of cheilitis was irritation, frequently caused by lip licking. But, almost one third was caused by ACD. Patients with chronic eczematous cheilitis should be patch-tested to identify the materials causing ACD.

Keyword

Allergic contact dermatitis; Cheilitis; Irritant contact dermatitis

MeSH Terms

Cheilitis*
Dermatitis, Allergic Contact
Dermatitis, Contact
Dermatology
Female
Humans
Incheon
Lip
Lip Diseases
Patch Tests*
Toothpastes
Toothpastes
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