Korean J Pathol.  2013 Dec;47(6):569-574.

Development of Six Tumors in a Sebaceus Nevus of Jadassohn: Report of a Case

  • 1Department of Pathology, Ankara Training and Research Hospital, Ankara, Turkey.
  • 2Department of Family Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. hulyayikilkan@hotmail.com
  • 3Department of Family Medicine, University of Antwerp, Antwerp, Belgium.


Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprised of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual for more than four tumors to arise simultaneously within a single sebaceus nevus. Here in, we report a case of a 70-year-old woman with six neoplastic proliferations including a syringocystadenoma papilliferum, pigmented trichoblastoma, tubular apocrine adenoma, sebaceoma, tumors of follicular infundibulum and superficial epithelioma with sebaceus differentiation arising in a long standing nevus sebaceus on the scalp. Our case is extraordinary because a single nevus sebaceus contained six neoplastic proliferations with differentiation toward the folliculosebaceous-apocrine unit.


Syringocystadenoma papilliferum; Pigmented trichoblastoma; Tubular apocrine adenoma; Sebaceous differentiation; Nevus sebaceous of Jadassohn
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