J Korean Cancer Assoc.  1997 Dec;29(6):1114-1118.

Primary Squamous Cell Carcinoma of the Breast

• Lee KG
• Lee KM
• Yun KJ

Abstract

The primary squamous cell carcinoma of the breast is an extremely rare neoplasm. The pathogenesis of the squamous cell carcinoma of the breast is puzzling because epithelial elements are not normally identified in breast tissue. It has been suggested that epithelial cells are derived from epidermoid cysts deposited during early embryological development, from metaplastic transformation of ductal cells, or after trauma or surgical manipulation. It must be carefully separated from lesions involving the epidermis and/or nipple region which must be considered as squamous carcinoma of the skin or dermal appendages. Also, it must be regarded as a separate entity distinct from adenocarcinoma of the breast with squamous cell metaplasia. We experienced a case of the primary squamous cell carcinoma and reported with a review the related literature briefly.

Keyword

Primary squamous cell carcinoma; Breast

MeSH Terms

Adenocarcinoma
Breast*
Carcinoma, Squamous Cell*
Epidermal Cyst
Epidermis
Epithelial Cells
Metaplasia
Nipples
Skin