Korean J Vet Res.  2011 Mar;51(1):65-68.

Neonatal isoerythrolysis in Thoroughbred foals

  • 1Korea Food & Drug Administration, Seoul 122-704, Korea.
  • 2College of Veterinary Medicine and Institute of Equine Medicine, Kyungpook National University, Daegu 702-701, Korea. chogj@knu.ac.kr
  • 3Jangsu Stud Farm, Korea Racing Authority, Jangsu 597-843, Korea.


Two 4-day-old Thoroughbred foals with acute clinical signs of depression, elevated pulse and respiratory rates, anemia, and jaundice were referred to the equine hospital of Korea Racing Authority. The foals were seemingly normal at birth, but showed clinical signs such as abnormal behavior, jaundice and anemia suddenly after ingestion of the mare's colostrum, followed by death at 4 days after birth. According to the results of the hematology, serum chemistry analysis, jaundice foal agglutination test, and blood groups test, the foals were diagnosed as neonatal isoerythrolysis (NI) caused by the mare's antibodies. These results suggested that the pregnant mares have a potential for NI.


blood type; neonatal isoerythrolysis; Thoroughbred foal
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