Korean J Urol.  2007 Jul;48(7):754-756. 10.4111/kju.2007.48.7.754.

Nested Variant of Transitional Cell Carcinoma with Hydronephrosis

Affiliations
  • 1Department of Urology, Hallym University College of Medicine, Chuncheon, Korea.

Abstract

The nested variant of transitional cell carcinoma(TCC) is rarely found in the bladder. Only about 80 such cases have been reported in the literature. Irregular nests and tubules of TCC infiltrating the lamina propria, with no involvement of the mucosal layer, characterize this disease. These characteristics make it difficult to diagnose the nested variant of transitional cell carcinoma. In this study we reported on a new case and review the relevant literature. This case was accompanied with hydronephrosis. We report on this case with its accompanying hydronephrosis because of its rarity and unusual histology, and also its prognostic significance emphasizes the need to distinguish it from classic TCC.

Keyword

Bladder; Transitional cell carcinoma; Nested; Variant

MeSH Terms

Carcinoma, Transitional Cell*
Hydronephrosis*
Mucous Membrane
Urinary Bladder

Figure

  • Fig. 1. Contrast-enhanced CT scan of the abdomen showed the right hydronephrosis, delayed nephrogram, perinephric infiltration (A) and focally enhancing wall thickening at the right posterolateral bladder wall, and this involved the right ureterovasical junction (UVJ) portion (B).

  • Fig. 2. Nested variant of the transitional cell bladder carcinoma. The tumor is growing as uniform round nests.


Reference

References

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