Korean J Med.
2004 Feb;66(2):200-203.
A case of bullous pyoderma gangrenosum associated with refractory acute biphenotypic leukemia
- Affiliations
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- 1Division of Hematology-Oncology, Department of Medicine, Yeungnam University College of Medicine, Daegu, Korea. hms@med.yu.ac.kr
- 2Department of Dermatology, Yeungnam University College of Medicine, Daegu, Korea.
- 3Department of Laboratory Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Abstract
- Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated acute leukemia. We report a case of pyoderma gangrenosum associated refractory acute biphenotypic leukemia wherein the malignant cells show a phenotype specific for myelogenous and lymphocytic leukemia. Histopathologic examination revealed moderate perivascular infiltrate consisting mainly of neutrophils and lymphocytes without involvement of leukemic cells in the skin lesions. Treatment with systemic steroid was followed by a characteristically rapid healing of the skin lesions.
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