Korean J Med.
2005 Mar;68(3):277-283.
The clinical significance of the differernce in left ventricular ejection fraction between rest and stress on gated myocardial perfusion SPECT
- Affiliations
-
- 1Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. hspark@knu.ac.kr
- 2Department of Nuclear Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Abstract
-
BACKGROUND: Gated myocardial perfusion SPECT improved diagnostic accuracy of coronary artery disease and enabled us to observe motion and thickening of myocardial walls, ejection fraction as well as myocardial perfusion. Many studies suggested that there was a decrease of left ventricular ejection fraction (LVEF) at post-stress compared with that at rest gated myocardial perfusion SPECT (stunning). The objective of this retrospective study is to evaluate the clinical significance of the decrease of LVEF at post-stress gated myocardial perfusion SPECT by correlating with coronary angiographic finding.
METHODS
Authors selected 41 patients who underwent exercise electrocardiography and gated myocardial perfusion SPECT between May, 2001 and May, 2002. The patients underwent coronary angiography within 6 months. The patients were divided into two groups, 16 patients in whom post-stress LVEF was >or=5% lower than rest (stunning group) and 25 patients in whom LVEF was not >or=5% lower than rest (non-stunning group).
RESULTS
The number of patients with hyperlipidemia was higher in stunning group than in non-stunning group (50% vs 4%, p=0.001). The number of patients with angiographic stenoses >90% was significantly higher in stunning group than in non-stunning group (75% vs 28%, p=0.04). The number of patients with multi-vessel disease was also significantly higher in stunning group than in non-stunning group (75% vs 36%, p=0.015).
CONCLUSION
The patients who had a decreased LVEF after stress (stunning) showed more severe coronary artery stenosis. This finding suggests that stunning may be an important additional indicator of underlying myocardial ischemia.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Gated Myocardial SPECT
- Post-stress Measurements of Left Ventricular Function With Gated Perfusion SPECT: Comparison with Resting Measurements by using Exercise and Adenosine Stress
- Comparison of Regional Myocardial Perfusion, Left Ventricular Volume and Ejection Fraction between 8- and 16-Frame Gated SPECT
- New Imaging Technique in Myocardial Perfusion SPECT
- Effects of Perfusion Defect on the Measurement of Left Ventricular Mass, Ventricular Volume and Post-stress Left Ventricular Ejection Fraction in Gated Myocardial Perfusion SPECT
