Korean J Hepatobiliary Pancreat Surg.  2011 May;15(2):123-127. 10.14701/kjhbps.2011.15.2.123.

Pancreatic Diabetes after Distal Pancreatectomy: Incidence Rate and Risk Factors

• Kim KJ
• Jeong CY
• Jeong SH
• Ju YT
• Jung EJ
• Lee YJ
• Choi SK
• Ha WS
• Park ST
• Hong SC

• KMID: 1980951
• DOI: http://doi.org/10.14701/kjhbps.2011.15.2.123

Abstract

PURPOSE
Pancreatectomy can impair production of endocrine and exocrine hormones. In this study, we evaluated: 1) the incidence rate of diabetes in patients undergoing distal pancreatectomy; 2) the correlation between the occurrence of pancreatic diabetes and the extent of the resected pancreas; and 3) factors associated with the development of pancreatic diabetes.
METHODS
We retrospectively reviewed the cases of 26 patients who could be compared in abdominal computed tomography before and after distal pancreatectomy for benign or malignant lesions between January, 1999 to June, 2010.
RESULTS
The incidence of pancreatic diabetes was 19.2%. Obese patients (BMI>25.0 kg/m2) had a higher incidence (p=0.029) of pancreatic diabetes after distal pancreatectomy than non-obese patients. The diabetes group had larger volumes of resected pancreas, but the difference was not statistically significant (p=0.105).
CONCLUSION
Several factors may be associated with the development of pancreatic diabetes after distal pancreatectomy. It is necessary to closely follow-up development of pancreatic diabetes regardless of the extent of resection.

Keyword

Pancreas; Diabetes mellitus; Postoperative diabetes; Distal pancreatectomy

MeSH Terms

Diabetes Mellitus
Follow-Up Studies
Humans
Incidence
Pancreas
Pancreatectomy
Retrospective Studies
Risk Factors

Figure

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  Fig. 1 Measurement of the volume of the pancreas. All pancreas areas were manually traced on every CT image section (arrow). We calculated the total volume of the pancreas and the residual volume after distal pancreatectomy.

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