Korean J Perinatol.  2009 Mar;20(1):69-73.

A case of normal delivery in a patient with aplastic anemia

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Yeungnam University, Daegu, Korea. yoonki@med.yu.ac.kr

Abstract

Aplastic anemia is a serious hematological disorder characterized by pancytopenia and bone marrow hypocellularity. Pregnancy associated with aplastic anemia is fortunately uncommon considering the significant morbidity and mortality for both mother and the fetus. The risk to the mother is mainly in the form of hemorrhage and sepsis, while the fetus may suffer from growth restriction and even intrauterine death. Maternal mortality has been reported variously from 20% to 60%. The relationship between pregnancy and aplastic anemia remains controversial. We experienced a patient with severe aplastic anemia in pregnancy who was treated with supportive transfusion of red blood cells and platelets. Here, we present a case with a brief review of the literature.

Keyword

Aplastic anemia; Pregnancy; Pancytopenia

MeSH Terms

Anemia, Aplastic
Blood Platelets
Bone Marrow
Erythrocytes
Fetus
Hemorrhage
Humans
Maternal Mortality
Mothers
Pancytopenia
Pregnancy
Sepsis
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